A new collagen membrane Striate+ (name change from CelGro Dental expected 2022) is getting positive results both within Australia and overseas. We found out what dental practitioners should know about this WA-developed, designed and manufactured product.
Striate+ is a membrane, derived from porcine collagen. With clearance for use in Australia (ARTG), the US (FDA 510k) and Europe (CE Mark), it is being used by dentists and oral surgeons both locally and internationally for:
Dr Brent Allan, oral and maxillofacial surgeon, says he routinely uses Striate+ in conjunction with bone grafting for dental implant treatment and guided bone regeneration for bone defects associated with impacted tooth removal and cyst enucleation.
Brent says the quality of bone healing in procedures where the Striate+ has been used is excellent.
“Manufacturers of other collagen membranes often recommend two-stage procedures for bone grafting in conjunction with dental implant treatment, with healing periods between six to nine months.” With the Striate+ membrane Brent has consistently achieved mature bone healing in a period of four months.
Brent found the handling quality of the Striate+ to be superior to other membranes. “What we found with some of the other membrane brands, when wet with blood or saline, they become like tissue paper and are very difficult to handle,” he says. “They stick to instruments, to the bone and surrounding tissues, making it difficult to place the membrane in the ideal location for bone regeneration.
“With Striate+ we find that it has much better handling properties, so the membrane can be positioned over the bone and the dental implants, ideally without dislodgement.
“Striate+ is part of Orthocell’s collagen medical device platform which also includes Remplir™ for nerve regeneration and SmrtGraft™ for shoulder reconstruction surgery. There are publications and ongoing research projects in both these fields,” he adds.
Paul Anderson, Orthocell CEO and Founder, says the development of Striate+ has been a 10-year journey to design, develop and manufacture the Western Australian product, in conjunction with Professor Ming Hao Zheng, from The University of Western Australia.
“We are essentially a regenerative medicine company who develops biological devices for bone, nerve and tendon repair,” Paul says. “We came at this type of development from a cellular therapy approach.
“There have been a lot of products in dentistry being produced without really understanding the regenerative medicine concept. What people have tried to do is to create a barrier membrane to keep the soft tissue out and enable the bone to grow, so we have taken it a step further and developed a collagen-based medical device, which is biological in nature. We describe it as 'more than a barrier membrane', meaning the product we developed has osteoconductive activity, so it works with the bone that’s growing to keep the soft tissue out but to enhance the bone growth. What we saw in Dr Allan’s studies was more consistent, predictable, mature bone at an earlier time.”
Paul says the exciting results enabled them to distribute and engage with key opinion leaders globally.
“What is different about this product is it is Australian designed, developed and manufactured. It is from a regenerative medicine company, who understands the interaction between cells and scaffolds and membranes. Striate+ is manufactured from Australian raw material using a proprietary SMRT™ process which results in a high-quality collagen medical device.
“Some dentists might think a membrane is a membrane and a scaffold is a scaffold, but it’s not. We have done an exhaustive search of all the capabilities and characteristics of membranes available globally and a large degree do not handle well, degrade rapidly and result in unpredictable and inconsistent bone growth. We want people to know that Australia can produce the very best and manufacture the very best and the people ultimately benefiting will be the patients.”
“Bone grafting is often required to restore the alveolar ridge dimensions for implant treatment,’ Brent says.
“Bone grafting is also required in the management of orthognathic surgical cases. I will be discussing bone grafting techniques and guided bone regeneration using the latest collagen membrane technology.” Dr Brent Allan will be attending the ADAWA General Meeting on October 26 and will be presenting cases where he has used this technology.
More information orthocell.com/striate-au/
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